Then 8 mg orally 2 times a day (every 12 hours) for 1 to 2 days after the completion of chemotherapyBuy zofran Online from Canada Drugs Direct, an Online Canadian Pharmacy that provides the best quality products at a discounted rate for zofranAug 11, · Zofran (ondansetron) is an antinausea medication used to prevent and treat nausea and vomiting caused by cancer chemotherapy and to prevent vomiting and nausea after surgery Chemotherapy agents cause increased secretion of serotonin, which stimulates serotonin (5HT3) receptors in the brain, resulting in nausea and vomiting
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Ondansetron 8mg-Video with information about ondansetron (zofran) Side effects, uses, indications, contraindications, warnings, precautions, interactions, mechanism of acEmeset 8 tablets 8mg contain ondansetron that is used to control nausea and vomiting caused by cancer radiotherapy by preventing the stimulation of nausea and vomiting caused by this cancer treatment Radiotherapy is a cytotoxic cancer treatment that causes the release of serotonin (5HT) from the cells of the small intestine, which stimulates
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Apr 12, 10 · Ondansetron Orally Disintegrating Tablets USP, 8 mg are white to offwhite, round tablets debossed with '7' on one side and 'E' on the other side with an embossed circular edge 4 CONTRAINDICATIONS Ondansetron orally disintegrating tablets are contraindicated in patientsDosage is based on your medical condition and response to therapy The dosage for children may also be based on age and weight In patients with severe liver problems, the usual maximum dose is 8 milligrams in 24 hours Take this medication exactly as directedThis may reflect some reduction in first pass metabolism at higher oral doses Mean bioavailability in healthy male subjects, following the oral administration of a single 8mg tablet, is approximately 55 to 60%
Dosage Adjustment for Patients with Impaired Hepatic Function In patients with severe hepatic impairment (ChildPugh2 score of 10 or greater), a single maximal daily dose of 8 mg to be infused over 15 minutes beginning 30 minutes before the start ofOct 22, · Label ZOFRAN ondansetron hcl 8mg tablet, film coated NDC Code (s) Packager Advanced Rx Pharmacy of Tennessee, LLC This is a repackaged label Source NDC Code (s)Aug 05, · Ondansetron is a medicine used to prevent nausea and vomiting caused by surgery or cancer treatments It's in a class of medicines called serotonin 5HT 3 receptor antagonists Ondansetron works by
If you have severe liver problems, do not take more than 8 mg of Zofran (ondansetron) per day Zofran (ondansetron) may be taken as needed or at scheduled times Follow the directions on your prescription labelOndansetron is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy), radiation treatment, or drugs used to put you to sleep before surgeryOndansetron works by blocking one of the body's natural substances that causes vomitingOndansetron is available under the following different brand names Zofran, ZofranPoor liver function The maximum recommended dose for people with severe liver function impairment is 8 mg/day In these people, ondansetron is cleared from the body at half to onethird the rate as in healthy people The concentration of ondansetron in body tissues as opposed to plasma is also higher than in healthy people
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Ondansetron blocks the actions of chemicals in the body that can trigger nausea and vomiting Ondansetron is used to prevent nausea and vomiting that may be caused by surgery, cancer chemotherapy, or radiation treatment Ondansetron may be used for purposes not listed in this medication guideThen 8 mg orally 2 times a day (every 12 hours) for 1 to 2 days after the completion of chemotherapyEach 8 mg ondansetron orally disintegrating tablet, USP for oral administration contains 8 mg ondansetron base Each ondansetron orally disintegrating tablet, USP also contains the inactive ingredients aspartame, colloidal silicon dioxide, croscarmellose sodium, magnesium stearate, mannitol, strawberry guarana flavor, and talc
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Chemotherapy, ondansetron tablets can be given to prevent nausea and vomitingOndansetron (Zofran) is a moderately priced drug used to treat nausea and vomiting caused by chemotherapy It is also used to prevent or treat nausea and vomiting after surgery This drug is more popular than comparable drugs It is available in both brand and generic formOndansetron Tablets 4 mg, 8 mg Safety Data Sheet according to Federal Register / Vol 77, No 58 / Monday, March 26, 12 / Rules and Regulations EN (English) SDS ID DrR_ 5/1 Carcinogenicity Suspected of causing cancer Ondansetron hydrochloride dihydrate Carcinogenic effects were not seen in 2year studies in
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Does ONDANSETRON ODT Interact with other Medications?Ondansetron 8 mg given orally twice daily was as effective as ondansetron 8 mg given orally three times daily In a randomised, double blind parallel group study, 406 patients were randomised to receive either ondansetron 16 mg suppository once daily for 3 days or ondansetron 8 mg orally twice daily for 3 daysWebMD provides common contraindications for ondansetron oral Find out what health conditions may be a health risk when taken with ondansetron oral
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Mar 04, 21 · For doses above 8mg the increase in ondansetron systemic exposure with dose is greater than proportional;Mar 15, 18 · Typical dosage for chemotherapy that's somewhat likely to cause nausea and vomiting 8 mg given 30 minutes before chemotherapy Four and eight hours after the first dose, your child can takeMay 28, 21 · Each 8mg Ondansetron Orally Disintegrating Tablet, USP for oral administration contains 8 mg ondansetron base Each Ondansetron Orally Disintegrating Tablet, USP also contains the inactive ingredients aspartame, colloidal silicon dioxide, crospovidone, magnesium stearate, mannitol, sodium stearyl fumarate and strawberry flavor
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Apr 14, · Ondansetron can be given either by rectal, oral (as an orodispersible tablet) intravenous or intramuscular administration For oral administration 8 mg taken 1 to 2 hours before chemotherapy or radiation treatment, followed by 8 mg every 12 hours for a maximum of 5 days to protect against delayed or prolonged emesisMay 05, 15 · An 8 mg ondansetron tablet was administered twice a day for 2 days after completion of chemotherapy † The first dose was administered 30 minutes before the start of emetogenic chemotherapy, with subsequent doses 4 and 8 hours after the first dose An 8 mg ondansetron tablet was administered 3 times a day for 2 days after completion ofThis medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy It is also used to prevent and treat nausea and vomiting after surgery Ondansetron works by blocking one of the body's natural substances (serotonin) that causes vomiting
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Angina, a type of chest pain dry mouth itching hives heart throbbing or pounding hiccups an inability to completely empty the bladder a feeling of pins and needles on skin anxious feelingsGeneric name Ondansetron oral Pronunciation (onDANsetron) Brand name (s) Zofran Uses This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy It is also used to prevent and treat nausea and vomiting after surgeryOndansetron 8 mg given orally twice daily was as effective as ondansetron 8 mg given orally three times daily In a randomised, double blind parallel group study, 406 patients were randomised to receive either ondansetron 16 mg suppository once daily for 3 days or ondansetron 8 mg orally twice daily for 3 days
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Oct 27, 14 · Phenylketonuric patients should be informed that ondansetron orally disintegrating tablets contain phenylalanine (a component of aspartame) Each 4 mg orally disintegrating tablet contains 168 mg phenylalanine and 8 mg orally disintegratingOndansetron is a carbazole derivative with antiemetic activity As a selective serotonin receptor antagonist, ondansetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy and radiotherapyinduced nausea and vomiting (NCI04)Nov 27, · Recommended dose 8 mg orally twice a day, with the first dose administered 30 minutes before the start of chemotherapy and the subsequent dose 8 hours later;
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Per the manufacturer, ondansetron dosage should not exceed 8 mg/day IV or PO in adult patients with severe hepatic impairment (ChildPugh score >= 10) In such patients, plasma clearance is reduced, resulting in a dramatically prolonged elimination halflife No specific pediatric recommendations are availableApr 26, 21 · Ondansetron 8 mg Tablets are white, circular, biconvex, film coated tablet marked '8' on one side and with a deep breakline on the other The breakline is only to facilitate breaking if necessary for ease of swallowing and not to divide into equal doses 4 Clinical particularsA single 8mg tablet, is approximately 56% Ondansetron systemic exposure does not increase proportionately to dose AUC from a 16mg tablet was 24% greater than predicted from an 8mg tablet dose This may reflect some reduction of firstpass metabolism at higher oral doses Bioavailability is also slightly enhanced by the
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Oct 26, · Recommended dose 8 mg orally twice a day, with the first dose administered 30 minutes before the start of chemotherapy and the subsequent dose 8 hours later;Severe Interactions These medications are not usually taken together Consult your healthcare professional (eg, doctor or pharmacist) forOf note, 4 and 8mg oral ondansetron tablets, orally disintegrating tablets (ODT), and oral solution are bioequivalent After a single 8 mg dose of ondansetron oral soluble film in adult patients, peak plasma concentrations are achieved in 13 hours, and mean Cmax is 3728 ng/mL and the mean AUC is 225 ng x hour/mL
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Nov 26, 19 · For most patients receiving emetogenic chemotherapy or radiotherapy, ondansetron 8 mg should be administered as a slow intravenous or intramuscular injection immediately before treatment, followed by 8 mg orally twelve hourly For oral administration 8 mg 12 hours before treatment, followed by 8 mg 12 hours later
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